If you’re someone who uses magic mushrooms, you may wonder if you can use this with cannabis. Doesn’t it change the mind-altering effects though? Will it cause a bad trip?
While the biochemistry between this is pretty simple, it’s not totally understood, and we’ll give you the answer here.
Can you mix cannabis and Psychedelics
Cannabis and fungi that’s psychedelic all come with natural compounds, the alkaloids and the cannabinoids. This is something that’s been used for a lot of reasons, including ceremonial, holistic, and are used to help expand the mind, or for recreational means. This is something that people may wonder if they can mix it, and some may wonder if they’re even compatible though.
Currently, there aren’t any clinical trials that have outlined whether or not this is safe or effective, some say that those products high in CBD are actually great for reducing the effects that shrooms might have. on the flip side, the higher THC may amplify the effects which are hallucinogenic as well.
Growing these together.
This is something that some people may wonder if they can grow together in harmony. The answer is you probably shouldn’t.
That’s because magic mushrooms need special care, especially since they need to be hydrated enough, and not contaminated. Weed is pretty simple, since you can put the seeds within the soil. On the flip side, mushroom cultivators need to properly sterilize the area. They sometimes use monotubes or even jars that are high in CO2 and humidity in order to keep those microbes that are contaminating out of there.
Cannabis on the flip side just needs lower humidity levels and higher levels of oxygen.
After you’ve harvested them first, you can transition this to a mushroom substrate, and also makes them far more resistant to various contaminants. You can also grow cannabis within a grow room for a second flush.

The growers that are usually doing this also may put mycelium around the plants, along with straw, mulch, or manure, and then you can get a second flush, since this is something that, minimally will just feed the soil area.
The Effects of both
Cannabis and shrooms both have different types of effects that come with this. Cannabis very high in THC actually creates a high, which comes with euphoria, open-mindedness, and creativity. The side effects are anxiety, dry mouth, and the munchies. Edibles also may be quite strong, sometimes psychedelic. Sometimes, paranoia increases with edibles, since they’re so high in concentrations.
On the contrast, shrooms are a bit different, since you want to go small with this, as it can enhance your senses and offer euphoria. Some people get total hallucinations, death to the ego, and sometimes people have a transient and complete reality disconnect in a few cases.

The shrooms have a psychedelic that does work with your serotonergic system, which means that when it’s metabolized, this is crated into a metabolite called psilocin, that binds to the receptors that are serotonin focus. Usually, the serotonin that is there improves the cognition. However, through tweaking this, it can be some way to change your cognition. On the contrast, the THC in cannabis works with the CB1 receptors, which do increase dopamine, improve the well-being, but also helps with anandamide uptake, which also increases serotonin.
So should you mix this? No, it will usually give you a bad trip. You should try to make sure that if you’re already sensitive to weed, you don’t do this, as it can lead to bad trips, and it can definitely make you panic if not careful.